HORDB

ID: hor006272
Uniprot ID: Q18060
Protein name: Probable insulin-like peptide gamma-type 1
Gene name: ins-11
Organism: Caenorhabditis elegans
Family: Insulin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa , Protostomia , Bilateria , Eumetazoa , Metazoa (kingdom), Opisthokonta , Eukaryota (superkingdom),cellular organisms
GO MF: NA
GO BP: GO:0045087 innate immune response
GO CC: GO:0005576 extracellular region

Sequence: APHHDKRHTACVLKIFKALNVMCNHEGDADVLRRTASDCCRESCSLTEMLASCTLTSSEESTRDI
Length: 65(27-91)
Propeptide: MSSYRQTLFILIILIVIILFVNEGQGAPHHDKRHTACVLKIFKALNVMCNHEGDADVLRRTASDCCRESCSLTEMLASCTLTSSEESTRDI
Signal peptide: MSSYRQTLFILIILIVIILFVNEGQG
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006272_AF2.pdb

hor006272_ESM.pdb

Mass:	835092	Formula:	C295H487N93O101S8
Absent amino acids:	QWY	Common amino acids:	SACLT
pI:	6.49	Basic residues:	12
Polar residues:	22	Hydrophobic residues:	18
Hydrophobicity:	-36.92	Boman Index:	-16140
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	70.62
Instability Index:	6434.31	Extinction Coefficient cystines:	375
Absorbance 280nm:	5.86

PubMed ID: 9851916
Title: Genome sequence of the nematode C. elegans: a platform for investigating biology.
PubMed ID: 9548970
Title: New insulin-like proteins with atypical disulfide bond pattern characterized in Caenorhabditis elegans by comparative sequence analysis and homology modeling.